◆主要學(xué)習(xí)工作經(jīng)歷

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1999年于四川大學(xué)化學(xué)工程系獲學(xué)士學(xué)位。

2003年于中國科學(xué)院水生生物研究所獲碩士學(xué)位。

2007年于日本信州大學(xué)獲博士學(xué)位。

2007年8月至2008年7月，美國克瑞頓大學(xué)，博士后。

2008年8月至2009年12月，美國貝勒大學(xué)，博士后。

2010年1月至2011年8月，美國大峽谷大學(xué)，博士后。

2011年9月-2024年3月，中國科學(xué)院南京地理與湖泊研究所，中國科學(xué)院“引進(jìn)國外杰出人才”計劃（中科院“百人計劃”）(A類)，研究員、博士生導(dǎo)師。

2024年4月至今，必威，研究員、博士生導(dǎo)師。

◆主要社會兼職

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生態(tài)毒理學(xué)報編委。

日本華僑華人博士協(xié)會理事。

◆主要研究內(nèi)容

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污染物在水體生境中的環(huán)境行為特征及其毒理效應(yīng)。

污染物在土壤生境中的環(huán)境行為特征及其毒理效應(yīng)。

生態(tài)毒理學(xué)研究的新技術(shù)和新方法及其應(yīng)用。

◆主要研究課題

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1) 湖泊微囊藻毒素主要異構(gòu)體產(chǎn)生和釋放機制研究(41877486), 62萬元, 2019.1~2022.12, 國家自然科學(xué)基金委員會, 國家自然科學(xué)基金面上項目, 主持.

2) 微囊藻毒素在水生生物食物鏈中的蓄積傳輸及魚類對其分解機制的研究(Y1S061), 70萬元, 2011.12~2014.12, 南京地理與湖泊研究所, 百人計劃啟動經(jīng)費, 主持.

3) 微囊藻毒素在水生食物網(wǎng)中的積累和分解(Y3BRO11050), 200萬元, 2013.6~2017.6, 中國科學(xué)院, 百人計劃, 主持.

4) 太湖水安全調(diào)控方案(2014ZX07101-011-02), 321萬元, 2014.1~2016.12, 科技部, 國家水體污染與控制重大專項子課題, 主持.

5) 太湖藻類和水生植物對水質(zhì)變化響應(yīng)研究(KZZD-EW-10-01-2), 225萬元, 2013.1~2016.12, 中國科學(xué)院, 中國科學(xué)院重點部署項目子課題, 主持.

6) 流域環(huán)境抗生素污染治理技術(shù)研究(Y7YZ051), 800萬元, 2017.5~2020.5, 中國科學(xué)院, 中國科學(xué)院重點部署項目, 參與.

7) 長江中下游水生態(tài)安全評估與保障重大戰(zhàn)略研究(Y7YZ011), 300萬元, 2017.1~2022.5, 中國科學(xué)院, 中國科學(xué)院任務(wù), 參與.

8) 湖泊水污染治理與生態(tài)景觀恢復(fù)技術(shù)研究示范(Y7STS51), 720萬元, 2017.11~2021.12, 中國科學(xué)院, 中國科學(xué)院重點部署項目, 參與.

9) 太湖水生態(tài)系統(tǒng)演變規(guī)律與調(diào)控技術(shù)研究(Y8SZX81), 387萬元, 2018.1~2021.12, 科技部, 國家水體污染與控制重大專項子課題, 主持.

10) 湖泊典型有機物的控制技術(shù)研發(fā)與示范(Y9STS011), 150萬元, 2019.1~2021.12, 中國科學(xué)院, 中國科學(xué)院區(qū)域重點項目, 主持.

◆主要研究成果

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1. 代表性論文（*為通訊作者）：

1) Zhang KY, Gu YR,Xue QJ, Xie LQ*. Changes in microcystin concentration in Lake Taihu, 13 years (2007–2020) after the 2007 drinking water crisis. Environmental Research, 2024, 241: 117597.

2) Xue QJ, Xie LQ*, Yang J, Yang J*, Su X. The prevalence and persistence of microcystin in seven subtropical reservoirs in China and associated potential risks for human health. Environmental Technology & Innovation. 2024, 33:103476.

3) Cheng, C., Steinman, A., Xue, Q., Zhang, L., Xie LQ*. The osmotic stress of Vallisneria natans (Lour.) Hara leaves originating from the disruption of calcium and potassium homeostasis caused by MC-LR. Water Research.2023, 245:120575.

4) Cheng C, Steinman AD, Xue QJ, Wang X, Xie LQ*. The disruption of calcium and hydrogen ion homeostasis of submerged macrophyte Vallisneria natans (Lour.) Hara caused by microcystin-LR. Aquatic Toxicology, 2023, 254: 106377.

5) Tang XN, Steinman AD, Xue QJ, Xu Y, Xie LQ*. Simultaneous electrochemical removal of Microcystis aeruginosa and sulfamethoxazole and its ecologic impacts on Vallisneria spiralis.  Science of The Total Environment, 2022, 815:152769.

6) Cheng Ch, Steinman AD, Zhang KY, Qin L, Xue QJ, Wang X, Xie LQ*. Risk assessment and identification of factors influencing the historical concentrations of microcystin in Lake Taihu, China. Journal of Environmental Sciences, 202, 127:1-14.

7) Zhang MCh, Steinman AD, Xue QJ, Zhao YY, Xu Y, Xie LQ*. Effects of erythromycin and sulfamethoxazole on Microcystis aeruginosa: Cytotoxic endpoints, production and release of microcystin-LR. Journal of Hazardous Materials, 2020, 399: 123021.

8) Wan X, Steinman AD,Gu YR, Zhu GW, Shu XB, Xue QJ, Zou W, Xie LQ*. Occurrence and risk assessment of microcystin and its relationship with environmental factors in lakes of the eastern plain ecoregion, China. Environmental Science and Pollution Research, 2020, 27(36): 45095-45107.

9) Xue QJ, Steinman AD, Xie LQ*, Yao L, Su XM, Cao Q, Zhao YY. Seasonal variation and potential risk assessment of microcystins in the sediments of Lake Taihu, China. Environmental Pollution, 2020, 259: 113884.

10) Cao Q, Wan X, Shu XB, Xie LQ*. Bioaccumulation and detoxication of microcystin-LR in three submerged macrophytes: The important role of glutathione biosynthesis. Chemosphere, 2019, 225: 935-942.

11) Xue QJ, Steinman AD, Xie LQ*, Yao L, Su XM, Cao Q, Zhao YY, Cai YJ. Seasonal variation and potential risk assessment of microcystins in the sediments of Lake Taihu, China. Environmental Pollution, 2019, 259: 113884.

12) Wan X, Steinman AD, Shu XB, Cao Q, Yao L; Xie LQ*. Combined toxic effects of microcystin-LR and phenanthrene on growth and antioxidant system of duckweed (Lemna gibba L.). Ecotoxicology and Environmental Safety, 2019, 185: 109668.

13) Su XM, Steinman AD, Oudsema M, Hassett M, Xie LQ*. The influence of nutrients limitation on phytoplankton growth and microcystins production in Spring Lake, USA. Chemosphere, 2019, 234: 34-42.

14) Cao Q, Liu WJ, Jiang WL, Shu XB, Xie LQ*. Glutathione biosynthesis plays an important role in microcystin-LR depuration in lettuce and spinach. Environmental Pollution, 2019, 253: 599-605.

15) Su XM, Steinman AD, Xue QJ, Zhao YY, Xie LQ*. Evaluating the contamination of microcystins in Lake Taihu, China: The application of equivalent total MC-LR concentration. Ecological Indicators, 2018, 89: 445-454.

16) Cao Q, Rediske RR, Yao L, Xie LQ*. Effect of microcystins on root growth, oxidative response, and exudation of rice (oryza sativa). Ecotoxicology and Environmental Safety, 2018, 149: 143-149.

17) Cao Q, Steinman AD, Wan X, Xie LQ*. Bioaccumulation of microcystin congeners in soil-plant system and human health risk assessment: A field study from Lake Taihu region of China. Environmental Pollution, 2018, 240:44-50.

18) Cao Q, Steinman AD, Wan X, Xie LQ*. Combined toxicity of microcystin-LR and copper on lettuce (Lactuca sativa L.). Chemosphere, 2018, 206: 474-482.

19) Cao Q, Steinman Alan D; Yao L, Xie LQ*. Effects of light, microorganisms, farming chemicals and water content on the degradation of microcystin-LR in agricultural soils. Ecotoxicology and Environmental Safety, 2018, 156: 141-147.

20) Cao Q, Steinman AD, Su XM, Xie LQ*. Effects of microcystins contamination on soil enzyme activities and microbial community in two typical lakeside soils. Environmental Pollution, 2017, 231: 134-142.

21) Su XM, Steinman AD, Tang XM, Xue QJ, Zhao YY, Xie LQ*. Response of bacterial communities to cyanobacterial harmful algal blooms in Lake Taihu, China. Harmful Algae, 2017, 68: 168-177.

22) Cao Q, Steinman AD, Yao L, Xie LQ*. Increment of root membrane permeability caused by microcystins result in more elements uptake in rice (Oryza saliva). Ecotoxicology and Environmental Safety, 2017, 145: 431-435.

23) Su XM, Steinman AD, Xue QJ, Zhao YY, Tang XM, Xie LQ*. Temporal patterns of phyto- and bacterioplankton and their relationships with environmental factors in Lake Taihu, China. Chemosphere, 2017, 184: 299-308.

24) Zhao YY, Cao Q, He YJ, Xue QJ, Xie LQ*, Yan YJ. Impairment of endoplasmic reticulum is involved in β-cell dysfunction induced by microcystin-LR. Environmental Pollution. 2017, 223, 587-594.

25) Zhao YY, Shi K, Su XM, Xie LQ*, Yan YJ. Microcystin-LR induces dysfunction of insulin secretion in ratinsulinoma (INS-1) cells: Implications for diabetes mellitus. Journal of Hazardous Materials, 2016, 314:11–21.

26) Xue QJ, Steinman AD, Su XM, Zhao YY, Xie LQ*, Temporal dynamics of microcystins dominant oligochaete of hypereutrophic Lake Taihu, China. Environmental Pollution, 2016, 213:585-593.

27) Zhao YY, Xue QJ, Su XM, Xie LQ*, Yan YJ, Steinman AD. First identification of the toxicity of microcystins on pancreatic islet function in humans and the involved potential biomarkers. Environmental Science and Technology, 2016，doi: 10.1021 /acs. est.5b03369.

28) Su XM, Xue QJ, Steinman AD, Zhao YY, Xie LQ*. Spatiotemporal dynamics of microcystin variants and relationships with environmental parameters in Lake Taihu, China. Toxins, 2015, 7(8):3224-3244.

29) Xie LQ, Yan W, Li J, Yu LQ, Wang JH, Li GY, Chen N, Steinman AD. Microcystin-RR exposure results in growth impairment by disrupting thyroid endocrine in zebrafish larvae. Aquatic Toxicology, 2015, 164:16-22.

2. 主要獲獎情況（省部級以上）：

· 2002年，中國科學(xué)院劉永齡獎。

· 2003年，湖北省優(yōu)秀論文獎。

· 2004年，日本文部省獎學(xué)金。

· 2013年，中國科學(xué)院“引進(jìn)國外杰出人才”計劃(中科院“百人計劃”)(A類)。

· 2017年，中國科學(xué)院優(yōu)秀百人計劃。

· 2018年，江蘇省333工程第三類培養(yǎng)人才。